超清版 GB/T 44480-2024 化学品 丽斑麻蜥急性经口毒性试验

ICS 13.300
CCS A 80
中华人民共和国国家标准
GB/T 44480—2024
化学品　丽斑麻蜥急性经口毒性试验
Chemicals—Eremias argus acute oral toxicity test
2024-09-29 发布2025-04-01 实施
国家市场监督管理总局
国家标准化管理委员会发 布

目　　次
前言 ····································································································· Ⅲ
1 范围 ·································································································· 1
2 规范性引用文件 ······················································································ 1
3 术语和定义 ··························································································· 1
4 试验概述 ······························································································ 1
5 试验方法 ······························································································ 2
5.1 材料和仪器 ······················································································ 2
5.2 样品制备 ························································································· 2
5.3 试验操作 ························································································· 2
5.4 结果计算与表示 ················································································· 3
5.5 质量保证和质量控制 ············································································· 3
6 试验报告 ······························································································ 3
附录 A （资料性）　丽斑麻蜥的驯养繁殖条件及方法录 A 方法 ········································ 4
附录 B （资料性）　溶液配制及试验观察记录表 ······················································· 7
参考文献 ·································································································· 8


前　　言
本文件按照GB/T 1.1—2020《标准化工作导则　第1 部分：标准化文件的结构和起草规则》的规
定起草。
请注意本文件的某些内容可能涉及专利。本文件的发布机构不承担识别专利的责任。
本文件由全国危险化学品管理标准化技术委员会（SAC/TC 251）提出并归口。
本文件起草单位：中国科学院生态环境研究中心、中检科健（天津）检验检测有限责任公司、中国
检验检疫科学研究院。
本文件主要起草人：常静、王会利、万斌、谢昀、李建中、周丽丽、刘春艳、王利利。
GB/T 44480—2024
Ⅲ

化学品　丽斑麻蜥急性经口毒性试验
1　范围
本文件描述了化学品对丽斑麻蜥急性经口毒性试验的试验方法，规定了试验的材料、条件、操作、
质量控制、数据处理、试验报告等的基本要求。
本文件适用于测试化学品对丽斑麻蜥的急性毒性效应。
2　规范性引用文件
下列文件中的内容通过文中的规范性引用而构成本文件必不可少的条款。其中，注日期的引用文
件，仅该日期对应的版本适用于本文件；不注日期的引用文件，其最新版本（包括所有的修改单）适用
于本文件。
GB/T 6682　分析实验室用水规格和试验方法
GB/T 31270.9—2014　化学农药环境安全评价试验准则　第9 部分：鸟类急性毒性试验
3　术语和定义
下列术语和定义适用于本文件。
3.1　
半数致死剂量　median lethal dose；LD50
一次给予实验用动物供试物后，引起实验用动物总体中半数死亡的毒物统计学剂量。以实验用动物
单位体重接受供试物的质量表示。
3.2　
最高无致死剂量　maximum non lethal dose；LD0
一次给予实验用动物供试物后，不引起实验用动物死亡的最高毒物统计学剂量。以实验用动物单位
体重接受供试物的质量表示。
3.3　
最低全致死剂量　minimum total lethal dose；LD100
一次给予实验用动物供试物后，引起实验用动物全部死亡的最低毒物统计学剂量。以实验用动物单
位体重接受供试物的质量表示。
3.4　
急性经口毒性　acute oral toxicity
一次经口给予实验用动物供试物后，动物在短期内（7 d）出现的健康损害效应。
3.5　
供试物　test substances
由各种元素组成的纯净物或混合物。
4　试验概述